Recombinant human JAZF1 protein

JAZF1 is a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. Recombinant human JAZF1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Juxtaposed with another zinc finger protein 1, TIP27, ZNF802

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

29.5 kDa (266aa)

Additionnal Information

JAZF1, juxtaposed with another zinc finger protein 1, TIP27, ZNF802, ATGP2072-10 µg, ATGP2072-20 µg, ATGP2072-50 µg, ATGP2072-100 µg, ATGP2072-250 µg, ATGP2072-500 µg, ATGP2072-1 mg, ATGP2072-10, ATGP2072-20, ATGP2072-50, ATGP2072-100, ATGP2072-250, ATGP2072-500, ATGP2072-1

References & Citations

Langberg, K.A., et al. (2012) J. Hum. Genet. 57 (1), 57-61; ; Nucci, M.R., et al. (2007) Am. J. Surg. Pathol. 31 (1), 65-70;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_778231

Uniprot Accession Number

Q86VZ6

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMTGIAAA SFFSNTCRFG GCGLHFPTLA DLIEHIEDNH IDTDPRVLEK QELQQPTYVA LSYINRFMTD AARREQESLK KKIQPKLSLT LSSSVSRGNV STPPRHSSGS LTPPVTPPIT PSSSFRSSTP TGSEYDEEEV DYEESDSDES WTTESAISSE AILSSMCMNG GEEKPFACPV PGCKKRYKNV NGIKYHAKNG HRTQIRVRKP FKCRCGKSYK TAQGLRHHTI NFHPPVSAEI IRKMQQ