Recombinant human PNOC protein

Prepronociceptin, also known as PNOC, is the ligand of the opioid receptor-like receptor (OPRL1) . It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. This protein may be involved in neuronal differentiation and development. Recombinant human PNOC protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Prepronociceptin, prepronociceptin, PPNOC

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

20.6 kDa (180aa)

Additionnal Information

PNOC, prepronociceptin, prepronociceptin, PPNOC, ATGP2069-10 µg, ATGP2069-20 µg, ATGP2069-50 µg, ATGP2069-100 µg, ATGP2069-250 µg, ATGP2069-500 µg, ATGP2069-1 mg, ATGP2069-10, ATGP2069-20, ATGP2069-50, ATGP2069-100, ATGP2069-250, ATGP2069-500, ATGP2069-1

References & Citations

Fiset M.E., et al. (2003) Biochemistry. 42:10498-10505; ; Nothacker H.-P., et al. (1996) Proc. Natl. Acad. Sci. u.S.A. 93:8677-8682;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_006219

Uniprot Accession Number

Q13519

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSSCQRDCL TCQEKLHPAL DSFDLEVCIL ECEEKVFPSP LWTPCTKVMA RSSWQLSPAA PEHVAAALYQ PRASEMQHLR RMPRVRSLFQ EQEEPEPGME EAGEMEQKQL QKRFGGFTGA RKSARKLANQ KRFSEFMRQY LVLSMQSSQR RRTLHQNGNV