Recombinant human CSDC2 protein

CSDC2, as known as cold shock domain-containing protein C2, is RNA-binding factor which binds specifically to the very 3'-uTR ends of both histone H1 and H3. 3 mRNAs, encompassing the polyadenylation signal. The cold shock domain containing proteins (CSDPs) are one group of the evolutionarily conserved nucleic acid-binding proteins widely distributed in bacteria, plants, animals, and involved in various cellular processes, including adaptation to low temperature, cellular growth, nutrient stress and stationary phase. It may play a central role in the negative regulation of histone variant synthesis in the developing brain. Recombinant human CSDC2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Cold shock domain-containing protein C2, dJ347H13.2, PIPPIN

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

19.2 kDa (176aa) confirmed by MALDI-TOF

Additionnal Information

CSDC2, Cold shock domain-containing protein C2, dJ347H13.2, PIPPIN, ATGP2064-10 µg, ATGP2064-20 µg, ATGP2064-50 µg, ATGP2064-100 µg, ATGP2064-250 µg, ATGP2064-500 µg, ATGP2064-1 mg, ATGP2064-10, ATGP2064-20, ATGP2064-50, ATGP2064-100, ATGP2064-250, ATGP2064-500, ATGP2064-1

References & Citations

Yang C. et al. (2012) PLoS One. 7:e32012; ; Park SJ. et al. (2009) Plant Cell Physiol. 50:869-878;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_055275

Uniprot Accession Number

Q9Y534

Species

Human

AA Sequence

MTSESTS PPVVPPLHSP KSPVWPTFPF HREGSRVWER GGVPPRDLPS PLPTKRTRTY SATARASAGP VFKGVCKQFS RSQGHGFITP ENGSEDIFVH VSDIEGEYVP VEGDEVTYKM CPIPPKNQKF QAVEVVLTQL APHTPHETWS GQVVGS