Recombinant human EHF protein
ETS homologous factor isoform 2, also known as EHF, is a distinct member of the ESE subfamily of Ets transcription factors. Ets factors constitute one important class of transcriptional regulators that play critical roles in hema-topoiesis, angiogenesis, organogenesis, oncogenesis and specification of neuronal connectivity. It is exclusively expressed in a subset of epithelial cells, with highest expression detected in glandular epithelium of the prostate, pancreas, salivary gland and trachea. EHF transactivates the c-Met promoter via three high affinity binding sites, which suggests that EHF may contribute to branching morphogenesis. Recombinant human EHF protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
ETS homologous factor isoform 2, ESE3, ESE3B, ESEJ
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
37.3 kDa (323aa)
Additionnal Information
References & Citations
Lin J H., et al. (1998) Cell. 95:393-407.; ; Kas K., et al. (2000) J Biol Chem. 275:2986-2998.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_036285
Uniprot Accession Number
Q9NZC4
Species
Human
AA Sequence
Frequently Asked Questions
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