Recombinant human HN1 protein
Hematological and neurological expressed 1 protein, also known as HN1, is a small protein that is highly conserved among species. HN1 expression is upregulated in regenerating neural tissues, including the axotomized adult rodent facial motor nerve and dedifferentiating retinal pigment epithelial cells of the Japanese newt. It is also expressed in numerous tissues during embryonic development as well as in regions of the adult brain that exhibit high plasticity. Recombinant human HN1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Hematological and neurological expressed 1 protein, ARM2, HN1A
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by BCA assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
18.1 kDa (174aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Additionnal Information
References & Citations
Laughlin K M., et al. (2009) Differentiation. 78 (1) :35-44; ; Zhou G., et al. (2004) Gene. 331:115-23.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol
Scientific Category
Neuroscience
NCBI Accession Number
NP_057269
Uniprot Accession Number
Q9UK76
Species
Human
AA Sequence
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