Recombinant human HN1 protein

Hematological and neurological expressed 1 protein, also known as HN1, is a small protein that is highly conserved among species. HN1 expression is upregulated in regenerating neural tissues, including the axotomized adult rodent facial motor nerve and dedifferentiating retinal pigment epithelial cells of the Japanese newt. It is also expressed in numerous tissues during embryonic development as well as in regions of the adult brain that exhibit high plasticity. Recombinant human HN1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Hematological and neurological expressed 1 protein, ARM2, HN1A

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by BCA assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

18.1 kDa (174aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

HN1, Hematological and neurological expressed 1 protein, ARM2, HN1A, ATGP2055-10 µg, ATGP2055-20 µg, ATGP2055-50 µg, ATGP2055-100 µg, ATGP2055-250 µg, ATGP2055-500 µg, ATGP2055-1 mg, ATGP2055-10, ATGP2055-20, ATGP2055-50, ATGP2055-100, ATGP2055-250, ATGP2055-500, ATGP2055-1

References & Citations

Laughlin K M., et al. (2009) Differentiation. 78 (1) :35-44; ; Zhou G., et al. (2004) Gene. 331:115-23.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol

Scientific Category

Neuroscience

NCBI Accession Number

NP_057269

Uniprot Accession Number

Q9UK76

Species

Human

AA Sequence

MTTTTTFKGV DPNSRNSSRV LRPPGGGSNF SLGFDEPTEQ PVRKNKMASN IFGTPEENQA SWAKSAGAKS SGGREDLESS GLQRRNSSEA SSGDFLDLKG EGDIHENVDT DLPGSLGQSE EKPVPAAPVP SPVAPAPVPS RRNPPGGKSS LVLG