Recombinant human MRM1 protein
Mitochondrial rRNA methyltransferase 1 homolog, also known as MRM1, probably methylates the ribose of guanosine G-2270 in the peptidyl transferase center of the mitochondrial large ribosomal RNA (21S) . Recombinant human MRM1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Mitochondrial rRNA methyltransferase 1 homolog, FLJ22578, Mitochondrial large ribosomal RNA ribose methylase
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
38.8 kDa (356aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Ota T., et al. (2004) Nat. Genet. 36:40-45
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT, 0.1mM PMSF
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_079140
Uniprot Accession Number
Q6IN84
Species
Human
AA Sequence
Frequently Asked Questions
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