Recombinant human MRI/CYREN protein

MRI, also known as modulator of retrovirus infection homolog isoform 1, characterizes the hamster ortholog and suggests that it may modulate the ability of the proteasome to degrade retroviral cores upon cellular infection. Recombinant human MRI protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

Modulator of retrovirus infection homolog isoform 1, MRI

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

19.2 kDa (180aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

MRI, Modulator of retrovirus infection homolog isoform 1, MRI, ATGP2037-10 µg, ATGP2037-20 µg, ATGP2037-50 µg, ATGP2037-100 µg, ATGP2037-250 µg, ATGP2037-500 µg, ATGP2037-1 mg, ATGP2037-10, ATGP2037-20, ATGP2037-50, ATGP2037-100, ATGP2037-250, ATGP2037-500, ATGP2037-1

References & Citations

Ota T. et al. (2004) Nat Genet. 36:40-45; ; Sjoblom T. et al. (2006) Science. 314:268-274.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl

Scientific Category

Enzymes & Proteases

NCBI Accession Number

NP_076938

Uniprot Accession Number

Q9BWK5

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMETLQSE TKTRVLPSWL TAQVATKNVA PMKAPKRMRM AAVPVAAARL PATRTVYCMN EAEIVDVALG ILIESRKQEK ACEQPALAGA DNPEHSPPCS VSPHTSSGSS SEEEDSGKQA LAPGLSPSQR PGGSSSACSR SPEEEEEEDV LKYVREIFFS