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Recombinant human OMP protein

Olfactory marker protein, also known as OMP, is uniquely associated with the mature olfactory receptor neurons in many vertebrate species from fish to man. It is expressed in the cytoplasm of olfactory chemosensory neurons in the nasal neuroepithelium. OMP expression is a sign of mature vertebrate olfactory receptor neurons (ORNs) . OMP may have a modulatory role in the odor detection/signal transduction cascade. In fetal olfactory epithelial cells, OMP is also a potent enhancer of mitosis, and it promotes an increase in uptake of tritiated thymidine in liver. Recombinant human OMP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Olfactory marker protein, Olfactory marker protein, olfactory neuronal-specific protein

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by BCA assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

21.3 kDa (186aa) confirmed by MALDI-TOF

Additionnal Information

OMP, Olfactory marker protein, Olfactory marker protein, olfactory neuronal-specific protein, ATGP2034-10 µg, ATGP2034-20 µg, ATGP2034-50 µg, ATGP2034-100 µg, ATGP2034-250 µg, ATGP2034-500 µg, ATGP2034-1 mg, ATGP2034-10, ATGP2034-20, ATGP2034-50, ATGP2034-100, ATGP2034-250, ATGP2034-500, ATGP2034-1

References & Citations

Buiakova O I., et al. (1996) Proc Natl Acad Sci uSA. 93:9858-9863; ; Behrens M., et al. (2003) J Neurochem. 86: 1289-1296.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT

Scientific Category

Neuroscience

NCBI Accession Number

NP_006180

Uniprot Accession Number

P47874

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAEDRPQ QPQLDMPLVL DQGLTRQMRL RVESLKQRGE KRQDGEKLLQ PAESVYRLNF TQQQRLQFER WNVVLDKPGK VTITGTSQNW TPDLTNLMTR QLLDPTAIFW RKEDSDAIDW NEADALEFGE RLSDLAKIRK VMYFLVTFGE GVEPANLKAS VVFNQL

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