Recombinant human ARPC2 protein

Actin-related protein 2/3 complex subunit 2, also known as ARPC2, belongs to the Rho family of small GTPases. This protein is one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein, the p34 subunit, has yet to be determined. Recombinant human ARPC2L protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Actin-related protein 2/3 complex subunit 2, ARC34, p34-Arc, PNAS-139, PRO2446

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

36.7 kDa (323aa) confirmed by MALDI-TOF

Additionnal Information

ARPC2, Actin-related protein 2/3 complex subunit 2, ARC34, p34-Arc, PNAS-139, PRO2446, ATGP2010-10 µg, ATGP2010-20 µg, ATGP2010-50 µg, ATGP2010-100 µg, ATGP2010-250 µg, ATGP2010-500 µg, ATGP2010-1 mg, ATGP2010-10, ATGP2010-20, ATGP2010-50, ATGP2010-100, ATGP2010-250, ATGP2010-500, ATGP2010-1

References & Citations

Mullins R D., et al. (1998) Proc Natl Acad Sci uSA. 95:6181-6186.; ; Syitkina T M., et al. (1999) J Cell Biol. 145:1009-1026.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 50% glycerol, 1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_005722

Uniprot Accession Number

O15144

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMILLEVN NRIIEETLAL KFENAAAGNK PEAVEVTFAD FDGVLYHISN PNGDKTKVMV SISLKFYKEL QAHGADELLK RVYGSFLVNP ESGYNVSLLY DLENLPASKD SIVHQAGMLK RNCFASVFEK YFQFQEEGKE GENRAVIHYR DDETMYVESK KDRVTVVFST VFKDDDDVVI GKVFMQEFKE GRRASHTAPQ VLFSHREPPL ELKDTDAAVG DNIGYITFVL FPRHTNASAR DNTINLIHTF RDYLHYHIKC SKAYIHTRMR AKTSDFLKVL NRARPDAEKK EMKTITGKTF SSR