Recombinant human ID2 protein

ID2 belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. Recombinant human ID2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Inhibitor of DNA binding 2, bHLHb26, GIG8, ID2A, ID2H, MGC26389

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

17 kDa (154aa)

Additionnal Information

ID2, Inhibitor of DNA binding 2, bHLHb26, GIG8, ID2A, ID2H, MGC26389, ATGP1991-10 µg, ATGP1991-20 µg, ATGP1991-50 µg, ATGP1991-100 µg, ATGP1991-250 µg, ATGP1991-500 µg, ATGP1991-1 mg, ATGP1991-10, ATGP1991-20, ATGP1991-50, ATGP1991-100, ATGP1991-250, ATGP1991-500, ATGP1991-1

References & Citations

Hara E. et al. (1994) J Biol Chem. 269:2139-2145.; ; Langlands Ket al. (1997) J Biol Chem. 272:19785-19793.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_002157

Uniprot Accession Number

Q02363

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF PSELMSNDSK ALCG