Recombinant human IL-34 protein

IL34, also known as Interleukin 34, is a protein belonging to a group of cytokines called interleukins. This protein increases growth or survival of immune cells known as monocytes; it elicits its activity by binding the Colony stimulating factor 1 receptor. It also has a potential role in viral infection, the adaptive immune response and bone marrow cell proliferation. Recombinant human IL34 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Interleukin-34 isoform 1, IL34, C16orf77, IL-34

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

29.6 kDa (260aa)

Additionnal Information

IL34, Interleukin 34, C16orf77, MGC34647, ATGP1990-10 µg, ATGP1990-20 µg, ATGP1990-50 µg, ATGP1990-100 µg, ATGP1990-250 µg, ATGP1990-500 µg, ATGP1990-1 mg, ATGP1990-10, ATGP1990-20, ATGP1990-50, ATGP1990-100, ATGP1990-250, ATGP1990-500, ATGP1990-1

References & Citations

Lin H. et al. (2008) Science. 320:807-811.; ; Wang Y. et al. (2012) Nat Immunol. 13:753-760.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Scientific Category

Hormones & Cytokines

NCBI Accession Number

NP_689669.1

Uniprot Accession Number

Q6ZMJ4

Species

Human

AA Sequence

NE PLEMWPLTQN EECTVTGFLR DKLQYRSRLQ YMKHYFPINY KISVPYEGVF RIANVTRLQR AQVSERELRY LWVLVSLSAT ESVQDVLLEG HPSWKYLQEV QTLLLNVQQG LTDVEVSPKV ESVLSLLNAP GPNLKLVRPK ALLDNCFRVM ELLYCSCCKQ SSVLNWQDCE VPSPQSCSPE PSLQYAATQL YPPPPWSPSS PPHSTGSVRP VRAQGEGLLP