Recombinant human IL-34 protein
IL34, also known as Interleukin 34, is a protein belonging to a group of cytokines called interleukins. This protein increases growth or survival of immune cells known as monocytes; it elicits its activity by binding the Colony stimulating factor 1 receptor. It also has a potential role in viral infection, the adaptive immune response and bone marrow cell proliferation. Recombinant human IL34 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Interleukin-34 isoform 1, IL34, C16orf77, IL-34
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
29.6 kDa (260aa)
Additionnal Information
References & Citations
Lin H. et al. (2008) Science. 320:807-811.; ; Wang Y. et al. (2012) Nat Immunol. 13:753-760.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea
Scientific Category
Hormones & Cytokines
NCBI Accession Number
NP_689669.1
Uniprot Accession Number
Q6ZMJ4
Species
Human
AA Sequence
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