Recombinant human SSR2 protein
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2) . The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. Recombinant human SSR2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Tanslocon-associated protein subunit beta precursor, Tanslocon-associated protein subunit beta precursor, HSD25, TLAP, TRAP-BETA, TRAPB
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
16.8 kDa (155aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Chinen K. et al. (1995) Cytogenet Cell Genet. 70:215-217.; ; Tajima S. et al. (1986) J Cell Biol. 103:1167-1178.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl
Scientific Category
Signal Transduction
NCBI Accession Number
NP_003136
Uniprot Accession Number
P43308
Species
Human
AA Sequence
EEGARLL ASKSLLNRYA VEGRDLTLQY NIYNVGSSAA LDVELSDDSF PPEDFGIVSG MLNVKWDRIA PASNVSHTVV LRPLKAGYFN FTSATITYLA QEDGPVVIGS TSAPGQGGIL AQREFDRRFS PHFLD
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