Recombinant human RASSF3 protein

Ras association domain-containing protein 3, also known as RASSF3, is a member of RASSF family. Members of the RASSF family contain a highly conserved Ras association domain (Ral GDS/AF-6 or RA) and function as Ras effectors/tumor suppressors. RASSF3 is a ubiquitously expressed protein found in normal and cancerous tissues. It contains an N-terminal RA domain and a coiled-coil SARAH domain. Three isoforms, namely RASSF3A, RASSF3B and RASSF3C, may exist for RASSF3 due to alternative splicing. RASSF3B and RASSF3C are shorter than RASSF3A and do not contain the RA and SARAH domain. Recombinant human RASSF3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Ras association domain-containing protein 3, MGC119194, MGC119195, MGC119197, Ras association (RalGDS/AF 6) domain family 3 antibody

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

30 kDa (261aa)

Additionnal Information

RASSF3, Ras association domain-containing protein 3, MGC119194, MGC119195, MGC119197, Ras association (RalGDS/AF 6) domain family 3 antibody, ATGP1984-10 µg, ATGP1984-20 µg, ATGP1984-50 µg, ATGP1984-100 µg, ATGP1984-250 µg, ATGP1984-500 µg, ATGP1984-1 mg, ATGP1984-10, ATGP1984-20, ATGP1984-50, ATGP1984-100, ATGP1984-250, ATGP1984-500, ATGP1984-1

References & Citations

Hesson L., et al. (2004) Oncogene. 23:2408-2419.; ; Tommasi S., et al. (2002) Oncogen. 21:2713-2720.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Cancer

NCBI Accession Number

NP_835463

Uniprot Accession Number

Q86WH2

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMSSGYSS LEEDAEDFFF TARTSFFRRA PQGKPRSGQQ DVEKEKETHS YLSKEEIKEK VHKYNLAVTD KLKMTLNSNG IYTGFIKVQM ELCKPPQTSP NSGKLSPSSN GCMNTLHISS TNTVGEVIEA LLKKFLVTES PAKFALYKRC HREDQVYACK LSDREHPLYL RLVAGPRTDT LSFVLREHEI GEWEAFSLPE LQNFLRILDK EEDEQLQNLK RRYTAYRQKL EEALREVWKP D