Recombinant human RASSF3 protein
Ras association domain-containing protein 3, also known as RASSF3, is a member of RASSF family. Members of the RASSF family contain a highly conserved Ras association domain (Ral GDS/AF-6 or RA) and function as Ras effectors/tumor suppressors. RASSF3 is a ubiquitously expressed protein found in normal and cancerous tissues. It contains an N-terminal RA domain and a coiled-coil SARAH domain. Three isoforms, namely RASSF3A, RASSF3B and RASSF3C, may exist for RASSF3 due to alternative splicing. RASSF3B and RASSF3C are shorter than RASSF3A and do not contain the RA and SARAH domain. Recombinant human RASSF3 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Ras association domain-containing protein 3, MGC119194, MGC119195, MGC119197, Ras association (RalGDS/AF 6) domain family 3 antibody
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
30 kDa (261aa)
Additionnal Information
References & Citations
Hesson L., et al. (2004) Oncogene. 23:2408-2419.; ; Tommasi S., et al. (2002) Oncogen. 21:2713-2720.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Cancer
NCBI Accession Number
NP_835463
Uniprot Accession Number
Q86WH2
Species
Human
AA Sequence
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