Recombinant human GRP/LGALSL protein
Galectin-related protein, also known as LGALSL, is a 172 amino acid protein that contains one galectin domain. Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and also play a role in tumor progression, pre-mRNA splicing and apoptosis. However, LGALSL does not appear to bind carbohydrates or lactose because the critical residues required for binding are not conserved. Recombinant human LGALSL protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Galectin-related protein, GRP, Galectin like protein, HSPC159, Lectin galactoside-binding-like protein
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
21.4 kDa (195aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Zhou D., et al. (2008) Proteins. 71:1582-1588; ; Walti M A., et al. (2008) Proteins. 72: 804-808.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT
Scientific Category
Other
NCBI Accession Number
NP_054900
Uniprot Accession Number
Q3ZCW2
Species
Human
AA Sequence
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