Recombinant human DGCR6 protein
DGCR6 shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin. This protein is a candidate for involvement in DiGeorge syndrome pathology and in schizophrenia. Recombinant human DGCR6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Protein DGCR6, DiGeorge syndrome critical region gene 6
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
27 kDa (243aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Pfuhl T, Durr M, Spurk A, et al. (2005) . Hum Genet. 117 (1) :70-80.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol
Scientific Category
Stem Cell
NCBI Accession Number
NP_005666
Uniprot Accession Number
Q14129
Species
Human
AA Sequence
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