Recombinant human DGCR6 protein

DGCR6 shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin. This protein is a candidate for involvement in DiGeorge syndrome pathology and in schizophrenia. Recombinant human DGCR6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Protein DGCR6, DiGeorge syndrome critical region gene 6

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

27 kDa (243aa) confirmed by MALDI-TOF

Additionnal Information

DGCR6, Protein DGCR6, DiGeorge syndrome critical region gene 6, ATGP1979-10 µg, ATGP1979-20 µg, ATGP1979-50 µg, ATGP1979-100 µg, ATGP1979-250 µg, ATGP1979-500 µg, ATGP1979-1 mg, ATGP1979-10, ATGP1979-20, ATGP1979-50, ATGP1979-100, ATGP1979-250, ATGP1979-500, ATGP1979-1

References & Citations

Pfuhl T, Durr M, Spurk A, et al. (2005) . Hum Genet. 117 (1) :70-80.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol

Scientific Category

Stem Cell

NCBI Accession Number

NP_005666

Uniprot Accession Number

Q14129

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMERYAGA LEEVADGARQ QERHYQLLSA LQSLVKELPS SFQQRLSYTT LSDLALALLD GTVFEIVQGL LEIQHLTEKS LYNQRLRLQN EHRVLRQALR QKHQEAQQAC RPHNLPVLQA AQQRELEAVE HRIREEQRAM DQKIVLELDR KVADQQSTLE KAGVAGFYVT TNPQELMLQM NLLELIRKLQ QRGCWAGKAA LGLGGPWQLP AAQCDQKGSP VPP