Recombinant human OB-Cadherin/CDH11 protein
CDH11, also known as cadherin 11, is a member of the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. This protein is defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. Recombinant human CDH11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Cadherin 11 type 2, CAD11, CDHOB, OB, OSF-4, OB-cadherin (Osteoblast)
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
66.2 kDa (601aa)
Additionnal Information
References & Citations
Pishvaian MJ. et al. (1999) Cancer Res. 59:947-952.; ; Suzuki S. et al. (1991) Cell Regul. 2:261-270.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl
Scientific Category
Cancer
NCBI Accession Number
AAH13609.1
Uniprot Accession Number
Q96CZ9
Species
Human
AA Sequence
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
