Recombinant human OB-Cadherin/CDH11 protein
CDH11, also known as cadherin 11, is a member of the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. This protein is defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. Recombinant human CDH11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Cadherin 11 type 2, CAD11, CDHOB, OB, OSF-4, OB-cadherin (Osteoblast)
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
66.2 kDa (601aa)
Additionnal Information
References & Citations
Pishvaian MJ. et al. (1999) Cancer Res. 59:947-952.; ; Suzuki S. et al. (1991) Cell Regul. 2:261-270.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl
Scientific Category
Cancer
NCBI Accession Number
AAH13609.1
Uniprot Accession Number
Q96CZ9
Species
Human
AA Sequence
Frequently Asked Questions
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