Recombinant human DNAL1 protein
DNAL1 is an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. DNAL1 is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Alternate splicing results in multiple transcript variants. Recombinant human DNAL1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Dynein light chain 1 axonemal, Dynein light chain 1, axonemal, C14orf168, CILD16
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
23.9 kDa (213aa)
Additionnal Information
References & Citations
Horvath J, Fliegauf M, et al. (2005) . Am J Respir Cell Mol Biol. 33 (1) :41-7.; ; Lancaster MA, et al. (2009) . Curr Opin Genet Dev. 19 (3) :220-9.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Cytoskeleton
NCBI Accession Number
NP_113615
Uniprot Accession Number
Q4LDG9
Species
Human
AA Sequence
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
