Recombinant human AMSH-LP protein

STAMBPL1 is a zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains, but doesn't cleave 'Lys-48'-linked polyubiquitin chains. The JAMM motif is essential for the protease activity. Recombinant human STAMBPL1 protein, fused to His-tag at N-terminus was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

AMSH-like protease, AMSH-like protease, ALMalpha, AMSH-FP, AMSH-LP, bA399O19.2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

52.1 kDa (458aa)

Additionnal Information

AMSH-LP, AMSH-like protease, AMSH-like protease, ALMalpha, AMSH-FP, AMSH-LP, bA399O19.2, ATGP1955-10 µg, ATGP1955-20 µg, ATGP1955-50 µg, ATGP1955-100 µg, ATGP1955-250 µg, ATGP1955-500 µg, ATGP1955-1 mg, ATGP1955-10, ATGP1955-20, ATGP1955-50, ATGP1955-100, ATGP1955-250, ATGP1955-500, ATGP1955-1

References & Citations

Nakamura M, Tanaka N, et al. (2006) . Genes Cells. 11 (6) :593-606.; ; Kikuchi K, Ishii N, et al. (2003) . Biochem Biophys Res Commun. 306 (3) :637-43.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 0.1mM PMSF

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_065850

Uniprot Accession Number

Q96FJ0

Species

Human

AA Sequence

MDQPFTVN SLKKLAAMPD HTDVSLSPEE RVRALSKLGC NITISEDITP RRYFRSGVEM ERMASVYLEE GNLENAFVLY NKFITLFVEK LPNHRDYQQC AVPEKQDIMK KLKEIAFPRT DELKNDLLKK YNVEYQEYLQ SKNKYKAEIL KKLEHQRLIE AERKRIAQMR QQQLESEQFL FFEDQLKKQE LARGQMRSQQ TSGLSEQIDG SALSCFSTHQ NNSLLNVFAD QPNKSDATNY ASHSPPVNRA LTPAATLSAV QNLVVEGLRC VVLPEDLCHK FLQLAESNTV RGIETCGILC GKLTHNEFTI THVIVPKQSA GPDYCDMENV EELFNVQDQH DLLTLGWIHT HPTQTAFLSS VDLHTHCSYQ LMLPEAIAIV CSPKHKDTGI FRLTNAGMLE VSACKKKGFH PHTKEPRLFS ICKHVLVKDI KIIVLDLR