Recombinant human DNAM-1/CD226 protein

CD226 is a 65kDa glycoprotein expressed on the surface NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. This protein also plays a role in megakaryocytic cell maturation. Recombinant human CD226 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

CD226 antigen, CD226 antigen, DNAM-1, DNAM1, PTA1, TLiSA1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

29.4 kDa (259aa)

Additionnal Information

DNAM1, CD226, CD226 antigen, CD226 antigen, DNAM-1, DNAM1, PTA1, TLiSA1, ATGP1954-10 µg, ATGP1954-20 µg, ATGP1954-50 µg, ATGP1954-100 µg, ATGP1954-250 µg, ATGP1954-500 µg, ATGP1954-1 mg, ATGP1954-10, ATGP1954-20, ATGP1954-50, ATGP1954-100, ATGP1954-250, ATGP1954-500, ATGP1954-1

References & Citations

Liu, J., et al. (2012) J. Immunol. 188 (11), 5511-5520; ; Liu, R., et al. (2012) Mol. Biol. Rep. 39 (6), 6915-6922

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_006557

Uniprot Accession Number

Q15762

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSEEVLWHT SVPFAENMSL ECVYPSMGIL TQVEWFKIGT QQDSIAIFSP THGMVIRKPY AERVYFLNST MASNNMTLFF RNASEDDVGY YSCSLYTYPQ GTWQKVIQVV QSDSFEAAVP SNSHIVSEPG KNVTLTCQPQ MTWPVQAVRW EKIQPRQIDL LTYCNLVHGR NFTSKFPRQI VSNCSHGRWS VIVIPDVTVS DSGLYRCYLQ ASAGENETFV MRLTVAEGKT DNQYTLFVA