Recombinant human DNAM-1/CD226 protein
CD226 is a 65kDa glycoprotein expressed on the surface NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. This protein also plays a role in megakaryocytic cell maturation. Recombinant human CD226 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
CD226 antigen, CD226 antigen, DNAM-1, DNAM1, PTA1, TLiSA1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
29.4 kDa (259aa)
Additionnal Information
References & Citations
Liu, J., et al. (2012) J. Immunol. 188 (11), 5511-5520; ; Liu, R., et al. (2012) Mol. Biol. Rep. 39 (6), 6915-6922
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_006557
Uniprot Accession Number
Q15762
Species
Human
AA Sequence
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