Recombinant human Cathepsin S protein

Cathepsin S, also known as CTSS, is a member of the peptidase C1 family. This protein is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. CTSS can function as an elastase over a broad pH range in alveolar macrophages. Recombinant human CTSS protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

MGC3886, CTSS, CatS, Cathepsin S

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

38.1 kDa (336aa)

Additionnal Information

Cathepsin S, Cathepsin S, Cathepsin S, MGC3886, ATGP1951-10 µg, ATGP1951-20 µg, ATGP1951-50 µg, ATGP1951-100 µg, ATGP1951-250 µg, ATGP1951-500 µg, ATGP1951-1 mg, ATGP1951-10, ATGP1951-20, ATGP1951-50, ATGP1951-100, ATGP1951-250, ATGP1951-500, ATGP1951-1

References & Citations

Inagaki H., et al. (2007) J. Med. Chem. 50:2693-2699; ; Fengler A., et al. (1998) Protein Eng. 11:1007-1013

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Immunology

NCBI Accession Number

NP_004070

Uniprot Accession Number

P25774

Species

Human

AA Sequence

QLHKDPTLD HHWHLWKKTY GKQYKEKNEE AVRRLIWEKN LKFVMLHNLE HSMGMHSYDL GMNHLGDMTS EEVMSLMSSL RVPSQWQRNI TYKSNPNWIL PDSVDWREKG CVTEVKYQGS CGACWAFSAV GALEAQLKLK TGKLVSLSAQ NLVDCSTEKY GNKGCNGGFM TTAFQYIIDN KGIDSDASYP YKAMDQKCQY DSKYRAATCS KYTELPYGRE DVLKEAVANK GPVSVGVDAR HPSFFLYRSG VYYEPSCTQN VNHGVLVVGY GDLNGKEYWL VKNSWGHNFG EEGYIRMARN KGNHCGIASF PSYPEI