Recombinant human PIP4K2B protein
PIP4K2B catalyzes the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4, 5-bisphosphate. It is a member of the phosphatidylinositol-4-phosphate 5-kinase family. The amino acid sequence of PIP4K2B does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, PIP4K2B interacts with p55 TNF receptor. Recombinant human PIP4K2B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta, PI5P4KB, PIP5K2B, PIP5KIIB, PIP5KIIbeta
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
49.8 kDa (439aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Richardson JP, Wang M, et al. (2007) . Cell Signal. 19 (6) :1309-14.; ; Luoh SW, Venkatesan N, et al. (2004) . Oncogene. 23 (7) :1354-63.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Scientific Category
Metabolism
NCBI Accession Number
NP_003550
Uniprot Accession Number
P78356
Species
Human
AA Sequence
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Mouse N-acylneuraminate cytidylyltransferase (Cmas)
Recombinant Mouse N-acylneuraminate cytidylyltransferase (Cmas)
Recombinant Mouse N-acylneuraminate cytidylyltransferase (Cmas)
Recombinant Mouse N-acylneuraminate cytidylyltransferase (Cmas)