Recombinant human CD32a/FCGR2A protein
Low affinity immunoglobulin gamma Fc region receptor II-a, also known as FCGR2A, is a member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. This protein is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Recombinant human FCGR2A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
23.0 kDa (208aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Lu J., et al. (2008) Nature. 456:989-992; ; Rikova K., et al. (2007) Cell. 131:1190-1203
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 50% glycerol, 1mM DTT
Scientific Category
Immunology
NCBI Accession Number
AAH19931.1
Uniprot Accession Number
P12318
Species
Human
AA Sequence
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