Recombinant human CIAPIN1 protein

Anamorsin, also known as CIAPIN1, is primarily expressed in the cytoplasm of liver, pancreas and heart tissue cells and does not show any homology to known apoptosis regulatory molecules of the Bcl-2 or CASP families, or to signal transduction molecules. Expression of CIAPIN1 is dependent on growth factor stimulation. It is a ubiquitously expressed protein, and when it is overexpressed, it confers apoptotic resistance. Recombinant human CIAPIN1protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Anamorsin, DRE2, PRO0915

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

36 kDa (335aa)

Additionnal Information

CIAPIN1, Anamorsin, DRE2, PRO0915, ATGP1930-10 µg, ATGP1930-20 µg, ATGP1930-50 µg, ATGP1930-100 µg, ATGP1930-250 µg, ATGP1930-500 µg, ATGP1930-1 mg, ATGP1930-10, ATGP1930-20, ATGP1930-50, ATGP1930-100, ATGP1930-250, ATGP1930-500, ATGP1930-1

References & Citations

Shibayama H., et al. (2011) Am J Hum Genet. 88 (5) :608-15.; ; Hao Z., et al. (2005) Hybridoma. 24:141-145.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Cancer

NCBI Accession Number

NP_064709

Uniprot Accession Number

Q6FI81

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSMADFGIS AGQFVAVVWD KSSPVEALKG LVDKLQALTG NEGRVSVENI KQLLQSAHKE SSFDIILSGL VPGSTTLHSA EILAEIARIL RPGGCLFLKE PVETAVDNNS KVKTASKLCS ALTLSGLVEV KELQREPLTP EEVQSVREHL GHESDNLLFV QITGKKPNFE VGSSRQLKLS ITKKSSPSVK PAVDPAAAKL WTLSANDMED DSMDLIDSDE LLDPEDLKKP DPASLRAASC GEGKKRKACK NCTCGLAEEL EKEKSREQMS SQPKSACGNC YLGDAFRCAS CPYLGMPAFK PGEKVLLSDS NLHDA