Recombinant human FN3KRP protein

Ketosamine-3-kinase, also known as FN3KRP, catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Recombinant human FN3KRP protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Ketosamine-3-kinase, FN3KL, FN3K-related protein

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

36.8 kDa (332aa)

Additionnal Information

FN3KRP, Ketosamine-3-kinase, FN3KL, FN3K-related protein, ATGP1892-10 µg, ATGP1892-20 µg, ATGP1892-50 µg, ATGP1892-100 µg, ATGP1892-250 µg, ATGP1892-500 µg, ATGP1892-1 mg, ATGP1892-10, ATGP1892-20, ATGP1892-50, ATGP1892-100, ATGP1892-250, ATGP1892-500, ATGP1892-1

References & Citations

Collard F., et al. (2004) Biochem. J. 382:137-143; ; Oppermann F.S., et al. (2009) Mol. Cell. Proteomics. 8:1751-1764

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Metabolism

NCBI Accession Number

NP_078895

Uniprot Accession Number

Q9HA64

Species

Human

AA Sequence

MEELLRR ELGCSSVRAT GHSGGGCISQ GRSYDTDQGR VFVKVNPKAE ARRMFEGEMA SLTAILKTNT VKVPKPIKVL DAPGGGSVLV MEHMDMRHLS SHAAKLGAQL ADLHLDNKKL GEMRLKEAGT VGRGGGQEER PFVARFGFDV VTCCGYLPQV NDWQEDWVVF YARQRIQPQM DMVEKESGDR EALQLWSALQ LKIPDLFRDL EIIPALLHGD LWGGNVAEDS SGPVIFDPAS FYGHSEYELA IAGMFGGFSS SFYSAYHGKI PKAPGFEKRL QLYQLFHYLN HWNHFGSGYR GSSLNIMRNL VK