Recombinant human Fas Ligand/FASLG protein
Fas ligand, also known as FASLG, belongs to the tumor necrosis factor family and is the ligand for FAS. Both are transmembrane proteins. Interaction of FAS with this ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Defects in FASLG may be related to some cases of systemic lupus erythematosus (SLE) . Recombinant human FASLG protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
19.6 kDa (173aa)
Additionnal Information
References & Citations
Kirkin V., et al. (2007) Cell Death Differ. 14:1678-1687; ; Voss M., et al. (2009) BMC Immunol. 10:53-53
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_000630
Uniprot Accession Number
P48023
Species
Human
AA Sequence
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD31 / PECAM-1 (158-2B3), CF405S conjugate, 0.1mg/mL
Mucin 5AC (MUC5AC) (45M1), CF594 conjugate, 0.1mg/mL
Ep-CAM / CD326 (VU-1D9), CF514 conjugate, 0.1mg/mL
