Recombinant human IMPAD1 protein
Inositol monophosphatase 3, also known as IMPAD1, is a member of the inositol monophosphatase family. IMPAD1 is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP) . Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1. Recombinant human IMPAD1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Inositol monophosphatase 3, GPAPP, IMP 3, IMP-3, IMPA3
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
37.6 kDa (349aa)
Additionnal Information
References & Citations
Vissers L E., et al. (2011) Am J Hum Genet. 88 (5) :608-15.; ; Kalujnaia S., et al. (2010) FASEB J. 24 (10) :3981-91.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol
Scientific Category
Metabolism
NCBI Accession Number
NP_060283
Uniprot Accession Number
Q9NX62
Species
Human
AA Sequence
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Exosome Isolation Kit from Cell Culture Media by Precipitation Method