Recombinant human sFRP-3/FRZB protein

FRZB is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility. Recombinant human FRZB protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

SRFP3, SFRP3, Secreted frizzled-related protein 3, OS1, hFIZ, FZRB, FRZB-PEN, FRZB1, FRZB, FRP-3, FRITZ, FRE

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

35 kDa (316aa)

Additionnal Information

FRE, FRITZ, FRP 3, FRP3, FRP-3, FRZB, FRZB 1, FRZB1, FRZB-1, FRZB-PEN, FZRB, hFIZ, OS1, Secreted frizzled related protein 3, Secreted frizzled-related protein 3, SFRP 3, SFRP3, SFRP-3, SRFP 3, SRFP3, SRFP-3, ATGP1888-10 µg, ATGP1888-20 µg, ATGP1888-50 µg, ATGP1888-100 µg, ATGP1888-250 µg, ATGP1888-500 µg, ATGP1888-1 mg, ATGP1888-010, ATGP1888-020, ATGP1888-050, ATGP1888-100, ATGP1888-250, ATGP1888-500, ATGP1888-01M

References & Citations

Baker-Lepain JC, Lynch JA, et al. (2012) . Arthritis Rheum. 64 (5) :1457-65. ; ; Ekstrom EJ, Sherwood V, et al. (2011) . PLoS One. 6 (4) :e18674.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Stem cell

NCBI Accession Number

NP_001454

Uniprot Accession Number

Q92765

Species

Human

AA Sequence

AACEPVR IPLCKSLPWN MTKMPNHLHH STQANAILAI EQFEGLLGTH CSPDLLFFLC AMYAPICTID FQHEPIKPCK SVCERARQGC EPILIKYRHS WPENLACEEL PVYDRGVCIS PEAIVTADGA DFPMDSSNGN CRGASSERCK CKPIRATQKT YFRNNYNYVI RAKVKEIKTK CHDVTAVVEV KEILKSSLVN IPRDTVNLYT SSGCLCPPLN VNEEYIIMGY EDEERSRLLL VEGSIAEKWK DRLGKKVKRW DMKLRHLGLS KSDSSNSDST QSQKSGRNSN PRQARN