Recombinant human KLRG1 protein
KLRG1 belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. Cell surface expression of KLRG1 is up-regulated by expression of MHC class I molecules. Recombinant human KLRG1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Killer cell lectin-like receptor subfamily G member 1, 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
17 kDa (153aa)
Additionnal Information
References & Citations
Schwartzkopff S, Grundemann C, et al. (2007) . J Immunol. 179 (2) :1022-9.; ; Ibegbu CC, Xu YX, et al. (2005) . J Immunol. 174 (10) :6088-94.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_005801.3
Uniprot Accession Number
Q96E93
Species
Human
AA Sequence
LCQGSNY STCASCPSCP DRWMKYGNHC YYFSVEEKDW NSSLEFCLAR DSHLLVITDN QEMSLLQVFL SEAFCWIGLR NNSGWRWEDG SPLNFSRISS NSFVQTCGAI NKNGLQASSC EVPLHWVCKK VRL
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