Recombinant human Substance P/TAC1 protein
TAC1, also known as protachykinin 1, is a member of the tachykinin peptide hormone family. TAC1 are a family of peptides that have similar biologic activities and share a common C-terminal sequence, phe-X-gly-leu-met-NH2, but have distinct N-terminal sequences that convey receptor specificities. TAC1 is thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. It is known to induce behavioral responses and function as vasodilators and secretagogues. Recombinant human TAC1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
15.6 kDa (135aa)
Additionnal Information
References & Citations
Advenier C. et al. (1997) Eur Respir J. 10:1892-1906.; ; Bannon MJ. et al. (1992) Brain Res Mol Brain Res. 12:225-231.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 2M urea
Scientific Category
Neuroscience
NCBI Accession Number
NP_003173
Uniprot Accession Number
P20366
Species
Human
AA Sequence
EEIGA NDDLNYWSDW YDSDQIKEEL PEPFEHLLQR IARRPKPQQF FGLMGKRDAD SSIEKQVALL KALYGHGQIS HKRHKTDSFV GLMGKRALNS VAYERSAMQN YERRR
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