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Recombinant human Substance P/TAC1 protein

TAC1, also known as protachykinin 1, is a member of the tachykinin peptide hormone family. TAC1 are a family of peptides that have similar biologic activities and share a common C-terminal sequence, phe-X-gly-leu-met-NH2, but have distinct N-terminal sequences that convey receptor specificities. TAC1 is thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. It is known to induce behavioral responses and function as vasodilators and secretagogues. Recombinant human TAC1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

Protachykinin-1, Protachykinin 1, 4930528L02Rik, NK-1, NK1, Nka, Nkna, Neurokinin 2, Neurokinin A, Neurokinin alpha, Neuromedin L, Neuropeptide K, Substance P, Tachykinin precursor 1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

15.6 kDa (135aa)

Additionnal Information

TAC1, Protachykinin-1, Protachykinin 1, 4930528L02Rik, NK-1, NK1, Nka, Nkna, Neurokinin 2, Neurokinin A, Neurokinin alpha, Neuromedin L, Neuropeptide K, Substance P, Tachykinin precursor 1, ATGP1879-10 µg, ATGP1879-20 µg, ATGP1879-50 µg, ATGP1879-100 µg, ATGP1879-250 µg, ATGP1879-500 µg, ATGP1879-1 mg, ATGP1879-10, ATGP1879-20, ATGP1879-50, ATGP1879-100, ATGP1879-250, ATGP1879-500, ATGP1879-1

References & Citations

Advenier C. et al. (1997) Eur Respir J. 10:1892-1906.; ; Bannon MJ. et al. (1992) Brain Res Mol Brain Res. 12:225-231.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 2M urea

Scientific Category

Neuroscience

NCBI Accession Number

NP_003173

Uniprot Accession Number

P20366

Species

Human

AA Sequence

EEIGA NDDLNYWSDW YDSDQIKEEL PEPFEHLLQR IARRPKPQQF FGLMGKRDAD SSIEKQVALL KALYGHGQIS HKRHKTDSFV GLMGKRALNS VAYERSAMQN YERRR

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