Recombinant human XRCC3 protein

XRCC3, also known as RAD51-like, belongs to the RecA family and RAD51 subfamily. It participates in homologous recombination to maintain chromosome stability and repair DNA damage. This protein functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. Recombinant human XRCC3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Product Specifications

Product Name Alternative

X-ray repair cross complementing protein 3, RAD51-like

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

40 kDa (366aa)

Additionnal Information

XRCC3, X-ray repair cross complementing protein 3, RAD51-like, ATGP1876-10 µg, ATGP1876-20 µg, ATGP1876-50 µg, ATGP1876-100 µg, ATGP1876-250 µg, ATGP1876-500 µg, ATGP1876-1 mg, ATGP1876-10, ATGP1876-20, ATGP1876-50, ATGP1876-100, ATGP1876-250, ATGP1876-500, ATGP1876-1

References & Citations

Tebbs RS. et al. (1995) Proc Natl Acad Sci u S A. 92:6354-6358.; ; Miller KA. et al. (2002) J Biol Chem. 277:8406-8411.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_005423

Uniprot Accession Number

O43542

Species

Human

AA Sequence

MDLDLLDLNP RIIAAIKKAK LKSVKEVLHF SGPDLKRLTN LSSPEVWHLL RTASLHLRGS SILTALQLHQ QKERFPTQHQ RLSLGCPVLD ALLRGGLPLD GITELAGRSS AGKTQLALQL CLAVQFPRQH GGLEAGAVYI CTEDAFPHKR LQQLMAQQPR LRTDVPGELL QKLRFGSQIF IEHVADVDTL LECVNKKVPV LLSRGMARLV VIDSVAAPFR CEFDSQASAP RARHLQSLGA TLRELSSAFQ SPVLCINQVT EAMEEQGAAH GPLGFWDERV SPALGITWAN QLLVRLLADR LREEEAALGC PARTLRVLSA PHLPPSSCSY TISAEGVRGT PGTQSH