Recombinant human TIM-3/HAVCR2 protein
HAVCR2, also known as TIM3, belongs to the immunoglobulin superfamily. HACVR2 regulates macrophage activation. It Inhibits T-helper type 1 lymphocyte (Th1) -mediated auto- and alloimmune responses and promotes immunological tolerance. Recombinant human HAVCR2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
22.7 kDa (206aa)
Additionnal Information
References & Citations
Sanchez-Fueyo A., et al. (2003) Nat. Immunol. 4:1093-1101; ; Zhu C., et al. (2005) Nat. Immunol. 6:1245-1252;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
AAH63431
Uniprot Accession Number
Q8TDQ0
Species
Human
AA Sequence
Frequently Asked Questions
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