Recombinant human JAM-B/VE-JAM protein
JAM2, also known as CD322, belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. JAM2 is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Recombinant human JAM2 protein, fused to His-tag at N-terminus, was expressed in E. coli
Product Specifications
Product Name Alternative
Junctional adhesion molecule B, C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
26.7 kDa (241aa)
Additionnal Information
References & Citations
Zhang Z., et al. (2004) Protein Sci. 13:2819-2824; ; Liu T., et al. (2005) J. Proteome Res. 4:2070-2080;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Scientific Category
Cytoskeleton
NCBI Accession Number
NP_067042
Uniprot Accession Number
P57087
Species
Human
AA Sequence
Frequently Asked Questions
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