Recombinant human JAM-B/VE-JAM protein

JAM2, also known as CD322, belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. JAM2 is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Recombinant human JAM2 protein, fused to His-tag at N-terminus, was expressed in E. coli

Product Specifications

Product Name Alternative

Junctional adhesion molecule B, C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE, Denatured

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

26.7 kDa (241aa)

Additionnal Information

JAM-B, VE-JAM, Junctional adhesion molecule B, C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM, ATGP1874-10 µg, ATGP1874-20 µg, ATGP1874-50 µg, ATGP1874-100 µg, ATGP1874-250 µg, ATGP1874-500 µg, ATGP1874-1 mg, ATGP1874-10, ATGP1874-20, ATGP1874-50, ATGP1874-100, ATGP1874-250, ATGP1874-500, ATGP1874-1

References & Citations

Zhang Z., et al. (2004) Protein Sci. 13:2819-2824; ; Liu T., et al. (2005) J. Proteome Res. 4:2070-2080;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Scientific Category

Cytoskeleton

NCBI Accession Number

NP_067042

Uniprot Accession Number

P57087

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MGSLGYHKAY GFSAPKDQQV VTAVEYQEAI LACKTPKKTV SSRLEWKKLG RSVSFVYYQQ TLQGDFKNRA EMIDFNIRIK NVTRSDAGKY RCEVSAPSEQ GQNLEEDTVT LEVLVAPAVP SCEVPSSALS GTVVELRCQD KEGNPAPEYT WFKDGIRLLE NPRLGSQSTN SSYTMNTKTG TLQFNTVSKL DTGEYSCEAR NSVGYRRCPG KRMQVDDLNI S