Recombinant human HEBP1 protein
HEBP1 is an intracellular tetrapyrrole-binding protein. HEBP1 includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells. Recombinant human HEBP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Heme binding protein 1, HBP, HEBP
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
23.5 kDa (212aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Devosse, T., et al. (2011) J. Immunol. 187 (3), 1475-1485; ; Micaelo, N.M., et al. (2010) J. Mol. Graph. Model. 29 (3), 396-405;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl,30% glycerol, 1mM DTT
Scientific Category
Metabolism
NCBI Accession Number
NP_057071
Uniprot Accession Number
Q9NRV9
Species
Human
AA Sequence
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