Recombinant human LIN-7C protein

LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. It forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. Recombinant human LIN7C protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Lin-7 homolog C (C. elegans), LIN-7-C, LIN-7C, MALS-3, MALS3, VELI3, Mammalian lin-seven protein 3, Vertebrate lin-7 homolog 3

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

24.2 kDa (220aa) confirmed by MALDI-TOF

Additionnal Information

LIN7C, Lin-7 homolog C (C. elegans), LIN-7-C, LIN-7C, MALS-3, MALS3, VELI3, ATGP1837-10 µg, ATGP1837-20 µg, ATGP1837-50 µg, ATGP1837-100 µg, ATGP1837-250 µg, ATGP1837-500 µg, ATGP1837-1 mg, ATGP1837-10, ATGP1837-20, ATGP1837-50, ATGP1837-100, ATGP1837-250, ATGP1837-500, ATGP1837-1

References & Citations

Ng, M.C., et al. (2010) J. Clin. Endocrinol. Metab. 95 (5), 2418-2425; ; Lanktree, M., et al. (2008) Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (6), 945-951;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol

Scientific Category

Signal Transduction

NCBI Accession Number

NP_060832

Uniprot Accession Number

Q9NUP9

Species

Human

AA Sequence

MGCSHHHHHH SSGLVPRGSH MGSMAALGEP VRLERDICRA IELLEKLQRS GEVPPQKLQA LQRVLQSEFC NAVREVYEHV YETVDISSSP EVRANATAKA TVAAFAASEG HSHPRVVELP KTEEGLGFNI MGGKEQNSPI YISRIIPGGI ADRHGGLKRG DQLLSVNGVS VEGEHHEKAV ELLKAAQGKV KLVVRYTPKV LEEMESRFEK MRSAKRRQQT