Recombinant human Syntenin-2/SDCBP2 protein

SDCBP2 contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Recombinant human SDCBP2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Syndecan binding protein, SITAC, SITAC18, ST-2, Syntenin-2, Similar to TACIP18

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

34.0 kDa (315aa) confirmed by MALDI-TOF

Additionnal Information

SDCBP2, Syndecan binding protein, SITAC, SITAC18, ST-2, ATGP1824-10 µg, ATGP1824-20 µg, ATGP1824-50 µg, ATGP1824-100 µg, ATGP1824-250 µg, ATGP1824-500 µg, ATGP1824-1 mg, ATGP1824-10, ATGP1824-20, ATGP1824-50, ATGP1824-100, ATGP1824-250, ATGP1824-500, ATGP1824-1

References & Citations

Zimmermann, P. (2006) Biochim. Biophys. Acta 1761 (8), 947-956; ; Koroll, M., (2001) J. Biol. Chem. 276 (14), 10646-10654;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_001186713

Uniprot Accession Number

Q9H190

Species

Human

AA Sequence

MSSLYPS LEDLKVDQAI QAQVRASPKM PALPVQATAI SPPPVLYPNL AELENYMGLS LSSQEVQESL LQIPEGDSTA VSGPGPGQMV APVTGYSLGV RRAEIKPGVR EIHLCKDERG KTGLRLRKVD QGLFVQLVQA NTPASLVGLR FGDQLLQIDG RDCAGWSSHK AHQVVKKASG DKIVVVVRDR PFQRTVTMHK DSMGHVGFVI KKGKIVSLVK GSSAARNGLL TNHYVCEVDG QNVIGLKDKK IMEILATAGN VVTLTIIPSV IYEHMVKKLP PVLLHHTMDH SIPDA