Recombinant human NTB-A/SLAMF6 protein
SLAM family member 6, also known as SLAMF6, belongs to the SLAM family of immune cell receptors. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. SLAMF6 is expressed on NK-, T-, and B cells. It exhibits homotypic interactions and can associate with adaptor molecules such as SAP to modulate immune cell functions. Recombinant human SLAMF6 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
SLAM family member 6, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
25.5 kDa (228aa)
Additionnal Information
References & Citations
Freeman G J., et al. (1991) J EXP Med. 174:625-631.; ; Aversa G., et al. (1997) Immunol Cell Biol. 75:202-205.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing, 0.4M Urea, 10% glycerol
Scientific Category
Immunology
NCBI Accession Number
NP_001171643
Uniprot Accession Number
Q96DU3
Species
Human
AA Sequence
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