Recombinant human mannan-binding lectin/MBL2 protein
Mannose-binding protein C, also known as MBL2, is a member of the collectin family of patternrecognition molecules. MBL2 is a secreted glycoprotein that is synthesized as a 248 amino acid precursor. The Protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. Recombinant human MBL2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Product Specifications
Product Name Alternative
Mannose binding lectin 2, MBL, Collectin 1, Mannose-binding protein, COLEC1, MBP-C, MBP1, MBP, MBL
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE, Denatured
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
18 kDa (164aa)
Additionnal Information
References & Citations
Sastry K., et al. (1989) J Exp Med. 170:1175.; ; Larsen F., et al. (2004) J Biol Chem. 279:21302.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol, 0.2M Nacl
Scientific Category
Immunology
NCBI Accession Number
NP_000233
Uniprot Accession Number
P11226
Species
Human
AA Sequence
Frequently Asked Questions
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