Recombinant human HGAL/GCSAM protein

GCET2 is a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Recombinant human GCET2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Germinal center-associated signaling and motility protein, Germinal center B-cell-expressed transcript 2 protein, GCSAM, GCAT2, HGAL, GCET2

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 85% by SDS-PAGE

Molecular Weight

23 kDa (201aa) confirmed by MALDI-TOF

Additionnal Information

HGAL, Germinal center-associated signaling and motility protein, Germinal center B-cell-expressed transcript 2 protein, Germinal center B cell expressed transcript 2 protein, Germinal center associated signaling and motility protein, GCSAM, GCET2, GCET 2, GCAT2, GCAT 2, ATGP1807-10 µg, ATGP1807-20 µg, ATGP1807-50 µg, ATGP1807-100 µg, ATGP1807-250 µg, ATGP1807-500 µg, ATGP1807-1 mg, ATGP1807-010, ATGP1807-020, ATGP1807-050, ATGP1807-100, ATGP1807-250, ATGP1807-500, ATGP1807-01M

References & Citations

Cubedo E, Maurin M, et al. (2011) . FEBS J. 278 (17) :3065-75.; ; Temmins C, Zhao S, et al. (2011) . Appl Immunohistochem Mol Morphol. 19 (3) :266-72.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 1mM DTT

Scientific Category

Cancer

NCBI Accession Number

NP_689998

Uniprot Accession Number

Q8N6F7

Species

Human

AA Sequence

MGNSLLR ENRRQQNTQE MPWNVRMQSP KQRTSRCWDH HIAEGCFCLP WKKILIFEKR QDSQNENERM SSTPIQDNVD QTYSEELCYT LINHRVLCTR PSGNSAEEYY ENVPCKAERP RESLGGTETE YSLLHMPSTD PRHARSPEDE YELLMPHRIS SHFLQQPRPL MAPSETQFSH L