What is the catalog number for Recombinant human CLNS1A protein?

The catalog number for Recombinant human CLNS1A protein is ATGP1799-500.

What sizes are available for Recombinant human CLNS1A protein?

Recombinant human CLNS1A protein is available in the following size(s): 500 µg.

Is Recombinant human CLNS1A protein in stock?

Recombinant human CLNS1A protein is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant human CLNS1A protein

CLNS1A, also as known as, Methylosome subunit pICln, belongs to the pICln (TC 1. A. 47) family. CLNS1A protein has functions in multiple regulatory pathways. This protein interaction with Sm proteins inhibits their assembly on u RNA and interferes with snRNP biogenesis. It is Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. And this protein is also found associated with the plasma membrane where it functions as a chloride current regulator. Recombinant human CLNS1A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Methylosome subunit pICln, CLCI, CLNS1B, Icln

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

28.7 kDa (261aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Additionnal Information

CLNS1A, Methylosome subunit pICln, CLCI, CLNS1B, Icln, ATGP1799-10 µg, ATGP1799-20 µg, ATGP1799-50 µg, ATGP1799-100 µg, ATGP1799-250 µg, ATGP1799-500 µg, ATGP1799-1 mg, ATGP1799-10, ATGP1799-20, ATGP1799-50, ATGP1799-100, ATGP1799-250, ATGP1799-500, ATGP1799-1

References & Citations

Pu W.T., et al. (1999) Mol. Cell. Biol. 19:4113-4120; ; Friesen W.J., et al. (2001) Mol. Cell. Biol. 21:8289-8300;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 2mM DTT

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_001284

Uniprot Accession Number

P54105

Species

Human

AA Sequence

MGSHMSFLKS FPPPGPAEGL LRQQPDTEAV LNGKGLGTGT LYIAESRLSW LDGSGLGFSL EYPTISLHAL SRDRSDCLGE HLYVMVNAKF EEESKEPVAD EEEEDSDDDV EPITEFRFVP SDKSALEAMF TAMCECQALH PDPEDEDSDD YDGEEYDVEA HEQGQGDIPT FYTYEEGLSH LTAEGQATLE RLEGMLSQSV SSQYNMAGVR TEDSIRDYED GMEVDTTPTV AGQFEDADVD H