Recombinant human KIN17 protein

DNA/RNA-binding protein KIN17, also known as KIN17, is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. KIN17 is ubiqutiously expressed with the highest levels of expression in muscle, heart and testis. SV40-transformed fibroblasts overexpress KIN17, which interacts with Large T antigen and reduces T-antigen-dependent DNA replication. Recombinant human KIN17 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

DNA/RNA-binding protein KIN17, BTCD, KIN17, KIN

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.5 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

47.8 kDa (416aa) confirmed by MALDI-TOF

Additionnal Information

KIN17, DNA/RNA-binding protein KIN17, BTCD, KIN17, KIN, ATGP1797-10 µg, ATGP1797-20 µg, ATGP1797-50 µg, ATGP1797-100 µg, ATGP1797-250 µg, ATGP1797-500 µg, ATGP1797-1 mg, ATGP1797-10, ATGP1797-20, ATGP1797-50, ATGP1797-100, ATGP1797-250, ATGP1797-500, ATGP1797-1

References & Citations

Biard D S., et al. (1997) Radiat Res. 147:42-450; ; Mazin A., et al. (1994) Nucleic Acids Res. 22: 4335-4341.;

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_036443

Uniprot Accession Number

O60870

Species

Human

AA Sequence

MGKSDFL TPKAIANRIK SKGLQKLRWY CQMCQKQCRD ENGFKCHCMS ESHQRQLLLA SENPQQFMDY FSEEFRNDFL ELLRRRFGTK RVHNNIVYNE YISHREHIHM NATQWETLTD FTKWLGREGL CKVDETPKGW YIQYIDRDPE TIRRQLELEK KKKQDLDDEE KTAKFIEEQV RRGLEGKEQE VPTFTELSRE NDEEKVTFNL SKGACSSSGA TSSKSSTLGP SALKTIGSSA SVKRKESSQS STQSKEKKKK KSALDEIMEI EEEKKRTART DYWLQPEIIV KIITKKLGEK YHKKKAIVKE VIDKYTAVVK MIDSGDKLKL DQTHLETVIP APGKRILVLN GGYRGNEGTL ESINEKTFSA TIVIETGPLK GRRVEGIQYE DISKLA