Recombinant human SRA1 protein
Steroid receptor RNA activator 1, also known as SRA1, exists as both a RNA transcript and as stably expressed proteins. Also this protein mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2) . SRA1 enhances cellular proliferation and differentiation and promotes apoptosis in vivo. It may play a role in tumorigenesis. Recombinant human SRA1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Steroid receptor RNA activator 1, pp7684, SRA, SRAP, STRAA1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
18.7 kDa (170aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Lanz R B., et al. (1999) Cell. 97:17-27; ; Watanabe M., et al. (2001) EMBO J. 20: 1341-1352.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT
Scientific Category
Cancer
NCBI Accession Number
NP_001030312.2
Uniprot Accession Number
Q9HD15
Species
Human
AA Sequence
Available Sizes
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