Recombinant human TRAPPC2 protein

TRAPPC2 is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, this protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in TRAPPC2 are a cause of spondyloepiphyseal dysplasia tarda (SEDT) . Recombinant human TRAPPC2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

ZNF547L, TRS20, TRAPPC2P1, Trafficking protein particle complex subunit 2, Spondyloepiphyseal dysplasia late, SEDT, Sedlin, SEDL, MIP2A, hYP38334

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

18.8 kDa (163aa) confirmed by MALDI-TOF

Additionnal Information

TRAPPC2, Trafficking protein particle complex subunit 2, hYP38334, MIP2A, SEDL, SEDT, TRAPPC2P1, TRS20, ZNF547L, ATGP1795-10 µg, ATGP1795-20 µg, ATGP1795-50 µg, ATGP1795-100 µg, ATGP1795-250 µg, ATGP1795-500 µg, ATGP1795-1 mg, ATGP1795-10, ATGP1795-20, ATGP1795-50, ATGP1795-100, ATGP1795-250, ATGP1795-500, ATGP1795-1

References & Citations

Gecz J, Shaw MA, et al. (2003) . Gene. 27; ;320:137-44.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_055378

Uniprot Accession Number

P0DI81

Species

Human

AA Sequence

MSGSFYF VIVGHHDNPV FEMEFLPAGK AESKDDHRHL NQFIAHAALD LVDENMWLSN NMYLKTVDKF NEWFVSAFVT AGHMRFIMLH DIRQEDGIKN FFTDVYDLYI KFSMNPFYEP NSPIRSSAFD RKVQFLGKKH LLS